Description
What CAPETIZ is ?
CAPETIZis a cancer medicine used in the treatment of colon
cancer, metastatic colorectal cancer and advanced gastric
cancer in combination with a platinum based regimen. It is
used combination with docetaxel for the treatment of patients
with locally advanced or metastatic breast cancer after failure
of cytotoxic chemotherapy.
How CAPETIZ works?
CAPETIZ tablets should be swallowed whole with water
within 30 minutes after a meal. Capecitabine tablets are
cytotoxic drug. Follow applicable special handling and
disposal procedures. If capecitabine tablets must be cut or
crushed, this should be done by a professional trained in safe
handling of cytotoxic drugs using appropriate equipment and
safety procedures. Capecitabine tablets dose is calculated
according to body surface area
How to take CAPETIZ?
It is annon-cytotoxic fluoropyrimidinecarbamate, which
functions as an orally administered precursor of the cytotoxic
moiety 5-fluorouracil (5-FU). Capecitabine is activated via
several enzymatic steps. The enzyme involved in the final
conversion to 5-FU, thymidine phosphorylase (ThyPase), is
found in tumour tissues, but also in normal tissues, albeit
usually at lower levels. In human cancer xenograft models
capecitabine demonstrated a synergistic effect in
combination with docetaxel, which may be related to the
upregulation of thymidine phosphorylase by docetaxel.
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