Description
What GEFITIZ is?
GEFITIZ is a tyrosine kinase inhibitor used as first-line therapy to treat non-small cell lung carcinoma (NSCLC) that meets certain genetic mutation criteria.
How to take GEFITIZ ?
Take GEFITIZ by mouth with or without food as directed by your doctor, usually once daily. If you have trouble swallowing the tablet, you may place the tablet in a glass of water (4 to 8 ounces/120 to 240 milliliters). Stir well for 15 minutes. Drink all of the mixture right away.
How does GEFITIZ work?
GEFITIZ is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase that binds to the adenosine triphosphate (ATP)-binding site of the enzyme. GEFITIZ is the first selective inhibitor of the EGFR tyrosine kinase which is also referred to as Her1 or ErbB-1. By inhibiting EGFR tyrosine kinase, the downstream signaling cascades are also inhibited, resulting in inhibited malignant cell proliferation.
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